Dendrogenin A (DDA) is a ligand for liver X receptor (LXR), that induces the expression of sodium/iodine symporter, and increases iodine uptake. Dendrogenin A induces cell differentiation of MCF-7, and reactivates the function of lactating cells. Dendrogenin A induces the expressions of the TSH receptor, thyroid peroxidase, and thyroglobulin, and affects thyroid hormone generation. Dendrogenin A exhibits cytotoxicity in cancer cell B-CPAP and 8505c with IC50 of 4.1 and 6.2 µM. Dendrogenin A arrests the cell cycle at G0/G1 phase[1].
Molekulargewicht:
513.80
Reinheit:
96.7
CAS Nummer:
[1191043-85-2]
Formel:
C32H55N3O2
Target-Kategorie:
LXR
Anwendungsbeschreibung:
MCE Product type: Biochemical Assay Reagents
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