Incadronic acid inhibits growth of Dictyostelium discoideum with an IC50 of 1.6 µM. Incadronic acid binds the farnesyl diphosphate synthase (FPPS) in Leishmania major with the Ki of 23 nM. Incadronic acid inhibits the bone resorption and reduces bone loss, that can be used in osteoporosis research. Incadronic acid inhibits the proliferation of cells RAW264.7, PC-3 and MCF-7 with IC50 of 48 to 228.6 µM[1].
Molekulargewicht:
287.19
Reinheit:
98.03
CAS Nummer:
[124351-85-5]
Formel:
C8H19NO6P2
Target-Kategorie:
Bacterial
Anwendungsbeschreibung:
MCE Product type: Reference compound
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