LL-K8-22, CAS [[3034487-84-5]]

Produktübersicht

• Artikelname: LL-K8-22, CAS [[3034487-84-5]]
• Artikelnummer: MCE-HY-149209
• Hersteller Artikelnummer: HY-149209
• Alternativnummer: MCE-HY-149209-25MG,MCE-HY-149209-5MG,MCE-HY-149209-10MG,MCE-HY-149209-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

LL-K8-22 is a potent, selective and durable PROTAC CDK8-cyclin C dual degrader, with DC50 values of 2.52 and 2.64 µM, respectively. LL-K8-22 also suppresses STAT1 Ser 727 phosphorylation. LL-K8-22 inhibits E2F- and MYC-driven carcinogenic transcriptional programs. LL-K8-22 can be used for triplenegative breast cancer (TNBC) research. (Pink: Ligand for target protein (HY-168683), Black: Linker (HY-Y0340), Blue: Ligand for E3 ligase (HY-N2427)) [1].

Produkteigenschaften

• Molekulargewicht: 573.77
• Reinheit: 99.76
• CAS Nummer: [3034487-84-5]
• Formel: C37H43N5O
• Target-Kategorie: CDK,Early 2 Factor (E2F),PROTACs,STAT

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1