SLC26A3-IN-1 is an inhibitor of anion exchanger protein SLC26A3 (IC50=340 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea[1].
Molekulargewicht:
358.39
CAS Nummer:
[307552-53-0]
Formel:
C23H18O4
Target-Kategorie:
GLUT
Anwendungsbeschreibung:
MCE Product type: Reference compound
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