BAY 61-3606 (dihydrochloride), CAS [[648903-57-5]]

Produktübersicht

• Artikelname: BAY 61-3606 (dihydrochloride), CAS [[648903-57-5]]
• Artikelnummer: MCE-HY-14985
• Hersteller Artikelnummer: HY-14985
• Alternativnummer: MCE-HY-14985-5MG,MCE-HY-14985-100MG,MCE-HY-14985-25MG,MCE-HY-14985-50MG,MCE-HY-14985-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

BAY 61-3606 dihydrochloride is an orally available, ATP-competitive, reversible and highly selective Syk inhibitor with a Ki of 7.5 nM an IC50 of 10 nM[1]. BAY 61-3606 dihydrochloride reduces ERK1/2 and Akt phosphorylation in neuroblastoma cell[2]. BAY 61-3606 dihydrochloride induces a large decrease of Syk phosphorylation in K-rn cell lysates[3]. Bay 61-3606 dihydrochloride sensitizes TRAIL-induced apoptosis by downregulating Mcl-1 in breast cancer cells[4].

Produkteigenschaften

• Molekulargewicht: 463.32
• Reinheit: 99.45
• CAS Nummer: [648903-57-5]
• Formel: C20H20Cl2N6O3
• Target-Kategorie: Apoptosis,Syk

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound