Purinostat mesylate is a selective inhibitor of HDAC. Purinostat mesylate inhibits class I and class IIb HDACs with IC50s from 0.81 to 11.5 nM. Purinostat mesylate induces apoptosis and affects cell cycle of LAMA84 and 188 BL-2 cells, and shows potently anti-leukemia effects in vivo. Purinostat mesylate can be used for the research of lymphoblastic leukemia[1].
Molekulargewicht:
586.62
Reinheit:
99.45
CAS Nummer:
[2650188-32-0]
Formel:
C24H30N10O6S
Target-Kategorie:
Apoptosis,HDAC
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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