SSR126768A free base is an orally active antagonist for oxytocin receptor, with Ki of 0.44 nM. SSR126768A free base is a tocolytic agent, that antagonizes the Oxytocin (HY-17571)-induced intracellular Ca2+ increase and prostaglandin release in human uterine smooth muscle cells, inhibits thus the Oxytocin (HY-17571)-induced uterine contraction and delays parturition in pregnant rats in labor[1].
Molekulargewicht:
604.52
CAS Nummer:
[785048-28-4]
Formel:
C33H31Cl2N3O4
Target-Kategorie:
Oxytocin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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