AChE/GSK-3beta-IN-1, CAS [[2412364-73-7]] Preis auf Anfrage
Artikelnummer:
MCE-HY-150537
Hersteller Artikelnummer:
HY-150537
Alternativnummer:
MCE-HY-150537-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
AChE/GSK-3beta-IN-1 (compound GT15) is a potent, dual AChE/GSK-3beta inhibitor with IC50 values of 1.2, 149.8 and 22.4 nM for hAChE , hBChE and hGSK-3beta, respectively. AChE/GSK-3beta-IN-1 penetrates the blood-brain barrier (BBB). AChE/GSK-3beta-IN-1 has high kinase selectivity profiles for the CMGC kinase family. AChE/GSK-3beta-IN-1 occupies the ATP binding site of DYRK1A. AChE/GSK-3beta-IN-1 inhibits ROS expression and reduces oxidative stress. AChE/GSK-3beta-IN-1 can be used for Alzheimers disease research[1].
