S07-2010 is a potent pan-AKR1C (aldo-keto reductase family 1 member C) inhibitor, with IC50 values of 0.19, 0.36, 0.47, and 0.73 µM for AKR1C3, AKR1C4, AKR1C1 and AKR1C2, respectively. S07-2010 induces apoptosis in A549/DDP cells. S07-2010 strengthens the cytotoxicity of chemotherapeutic agents in drug-resistant cells. S07-2010 significantly inhibits the proliferation of drug-resistant cells[1].
Molekulargewicht:
371.45
Reinheit:
98.35
CAS Nummer:
[1223194-71-5]
Formel:
C19H21N3O3S
Target-Kategorie:
Aldose Reductase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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