Glutaminyl cyclases-IN-1 (IsoQC-IN-1) is a potent glutaminyl cyclases (QC) inhibitor with IC50 values of 12 nM and 73 nM for human QC and isoQC, respectively. Glutaminyl cyclases-IN-1 can selectively interfere with the interaction of CD47/SIRPalpha through isoQC inhibition, and enhances the increased phagocytic activity of both THP-1 and U937 macrophages[1].
Molekulargewicht:
478.61
Reinheit:
98.21
CAS Nummer:
[3032400-33-9]
Formel:
C25H30N6O2S
Target-Kategorie:
CD47
Anwendungsbeschreibung:
Reference compound
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