MEN 10207 (acetate) is a selective antagonist of the NK-2 tachykinin receptor. MEN 10207 (acetate) induces tachykinin-induced contractions in rat bladder and guinea pig airways in vivo. MEN 10207 (acetate) inhibits [beta-Ala 8 ]-NKA (4-10)-induced enhancement of bladder motility in anesthetized rats and [beta-Ala 8 ]-NKA (4-10)-induced enhancement of bronchoconstriction in anesthetized guinea pigs[1].
Molekulargewicht:
1109.24
Formel:
C57H68N14O10.xC2H4O2
Target-Kategorie:
Neurokinin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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