PXS-4787 hydrochloride is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 hydrochloride inhibits LOX with IC50s of 2 µM (Bovine LOX), 3.2 µM (rh LOXL1), 0.6 µM (rh LOXL2), 1.4 µM (rh LOXL3), 0.2 µM (rh LOXL4), respectively. PXS-4787 hydrochloride reduces deposition and crosslinking of collagen I secreted by human fibroblasts[1].
Molekulargewicht:
265.73
Reinheit:
99.71
CAS Nummer:
[2409964-40-3]
Formel:
C10H13ClFNO2S
Target-Kategorie:
Monoamine Oxidase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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