Bemcentinib (GMP), CAS [[1037624-75-1]] Preis auf Anfrage
Artikelnummer:
MCE-HY-15150G
Hersteller Artikelnummer:
HY-15150G
Alternativnummer:
MCE-HY-15150G-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
R428 (GMP), BGB324 (GMP)
Bemcentinib (R428) GMP is Bemcentinib (HY-15150) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy.Bemcentinib (R428) is a selective and orally active Axl inhibitor with an IC50 of 14 nM. Bemcentinib retards cancer cell migration and invasion. Bemcentinib exhibits >100-fold selectivity for Axl versus Abl and 50- and >100-fold selectivity over TAM family kinases Mer and Tyro3, respectively, in cells. Bemcentinib blocks tumor spread and prolongs survival in models of metastatic breast cancer[1][2].
Molekulargewicht:
506.64
CAS Nummer:
[1037624-75-1]
Formel:
C30H34N8
Target-Kategorie:
TAM Receptor
Anwendungsbeschreibung:
MCE Product type: GMP Small Molecules
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