Pyridostatin (RR82) TFA is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin TFA promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin TFA targets the proto-oncogene Src. Pyridostatin TFA reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells[1][2][3].
Molekulargewicht:
710.66
Reinheit:
99.54
CAS Nummer:
[1472611-44-1]
Formel:
C33H33F3N8O7
Target-Kategorie:
G-quadruplex
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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