Pyridostatin (RR82) trihydrochloride is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin trihydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin trihydrochloride targets the proto-oncogene Src. Pyridostatin trihydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells[1][2].
Molekulargewicht:
706.02
Reinheit:
98.06
CAS Nummer:
[2517456-88-9]
Formel:
C31H35Cl3N8O5
Target-Kategorie:
G-quadruplex
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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