cis-ICeD-2 is the cis isomer of ICeD-2 (HY-151871). ICeD-2 is a cell death inducer that induces cell death in HIV-1-infected cells. ICeD-2-mediated killing of HIV-1-infected cells is dependent on HIV-1 protease activity. ICeD-2 effectively blocks the hydrolysis of Gly-Pro-AMC by the dipeptidyl peptidases DPP8 and DPP9. ICeD-2 demonstrates strong stability against DPP9 in PBMCs.[1].
Molekulargewicht:
327.46
Formel:
C20H29N3O
Target-Kategorie:
Dipeptidyl Peptidase,Drug Isomer,HIV
Anwendungsbeschreibung:
MCE Product type: Reference compound
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