Glucocorticoid receptor modulator 1 is a highly potent and orally active non-steroidal selective glucocorticoid receptor modulator with an IC50 value of 9 nM and 130 nM for NF-kappaB and AP-1, respectively. Glucocorticoid receptor modulator 1 can effectively reduce the expression of inflammatory factors IL-6, IL-1beta, TNF-alpha, also can relieve dermatitis in mice[1].
Molekulargewicht:
470.97
Reinheit:
99.79
CAS Nummer:
[2868357-11-1]
Formel:
C24H23ClN2O4S
Target-Kategorie:
AP-1,Glucocorticoid Receptor,NF-kappaB
Anwendungsbeschreibung:
Reference compound
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