PPI-GIT1/beta-Pix interaction-IN-1 is a potent and orally active GIT1/beta-Pix protein-protein interaction (PPI) inhibitor with a KD value of 7.7 µM. PPI-GIT1/beta-Pix interaction-IN-1 disrupts the GIT/PIX interaction can impact the activation of the downstream Rho GTPase Rac1 and Cdc42. PPI-GIT1/beta-Pix interaction-IN-1 inhibits metastasis of gastric cancer[1].
Molekulargewicht:
391.42
Reinheit:
99.01
CAS Nummer:
[2070916-70-8]
Formel:
C23H21NO5
Target-Kategorie:
Ras
Anwendungsbeschreibung:
MCE Product type: Reference compound
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