BODIPY FL thalidomide is a high-affinity and selective human cereblon (CRBN)-targeting fluorescent probe with a Kd of 3.6 nM. BODIPY FL thalidomide enables use as a probe in time-resolved fluorescence resonance energy transfer (TR-FRET) binding assays for cereblon ligands. BODIPY FL thalidomide supports development of highly sensitive, selective, stable cereblon TR-FRET binding assays (Ex/Em = 502/510 nm)[1].
Molekulargewicht:
732.58
Reinheit:
99.18
CAS Nummer:
[2740620-18-0]
Formel:
C37H43BF2N6O7
Target-Kategorie:
Fluorescent Dye,Ligands for E3 Ligase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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