CP-640186 is an orally active and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 can also stimulate muscle fatty acid oxidation[1][2].
Molekulargewicht:
485.62
Reinheit:
99.72
CAS Nummer:
[591778-68-6]
Formel:
C30H35N3O3
Target-Kategorie:
Acetyl-CoA Carboxylase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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