JAK-IN-24 is a JAK inhibitor, with IC50s of 0.534 and 24 nM at the presence of 4 µM or 1mM ATP, respectively. JAK-IN-24 also inhibits PBMC IL-15 induced STAT5 phosphorylation with an IC50 of 86.171 nM[1]. JAK-IN-24 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molekulargewicht:
367.44
Reinheit:
99.35
CAS Nummer:
[2042629-43-4]
Formel:
C20H25N5O2
Target-Kategorie:
JAK
Anwendungsbeschreibung:
MCE Product type: Reference compound
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