HEC96719 is a selective and orally active tricyclic farnesoid X receptor (FXR) agonist with EC50 values of 1.37 and 1.55 nM by time-resolved fluorescence energy transfer (TR-FRET) and luciferase reporter assays, respectively. HEC96719 significantly improves non-alcoholic steatohepatitis (NASH) and liver fibrosis with favorable tissue distribution in liver and intestine. HEC96719 can be used for the research of non-alcoholic steatohepatitis[1].
Molekulargewicht:
549.40
Reinheit:
98.01
CAS Nummer:
[2181834-03-5]
Formel:
C29H22Cl2N2O5
Target-Kategorie:
FXR
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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