QR-6401 is an orally active and selective macrocyclic CDK2 inhibitor with IC50 values of 0.37, 10, 22, 34 and 45 nM for CDK2/E1, CDK9/T1, CDK1/A2, CDK6/D3 and CDK4/D1, respectively. QR-6401 has potent antitumor activity in an OVCAR3 ovarian cancer xenograft model. QR-6401 has the potential to be used in the study of cancer[1].
Molekulargewicht:
369.42
CAS Nummer:
[2845096-18-4]
Formel:
C19H23N5O3
Target-Kategorie:
CDK
Anwendungsbeschreibung:
MCE Product type: Reference compound
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