Elironrasib, CAS [[2641998-63-0]]

Produktübersicht

• Artikelname: Elironrasib, CAS [[2641998-63-0]]
• Artikelnummer: MCE-HY-153346
• Hersteller Artikelnummer: HY-153346
• Alternativnummer: MCE-HY-153346-25MG,MCE-HY-153346-1MG,MCE-HY-153346-5MG,MCE-HY-153346-10MMX1ML,MCE-HY-153346-10MG,MCE-HY-153346-100MG,MCE-HY-153346-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: RMC-6291

Produktbeschreibung

Elironrasib is an orally active and covalent inhibitor of KRASG12C(ON). Elironrasib forms a tri-complex within tumor cells between KRASG12C(ON) and cyclophilin A (CypA). Thus, Elironrasib prevents KRASG12C(ON) from signaling via steric blockade of RAS effector binding. Elironrasib inhibits ERK signaling and induced apoptosis in KRASG12C-mutant H358 cells. Elironrasib also inhibits the proliferation of KRASG12C mutant cells with a median IC50 of 0.11 nM[1][2].

Produkteigenschaften

• Molekulargewicht: 1012.26
• Reinheit: 99.65
• CAS Nummer: [2641998-63-0]
• Formel: C55H78FN9O8
• Target-Kategorie: Apoptosis,ERK,Ras

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound