Timapiprant sodium (OC000459 sodium) is a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known as CRTH2) antagonist. Timapiprant sodium (OC000459 sodium) potently displaces [3H] PGD2 from human recombinant DP2 (Ki=13 nM), rat recombinant DP2 (Ki=3 nM), and human native DP2 (Ki=4 nM). Timapiprant sodium (OC000459 sodium) inhibits mast cell activation of Th2 lymphocytes and eosinophils[1].
Molekulargewicht:
370.35
Reinheit:
99.61
CAS Nummer:
[950688-14-9]
Formel:
C21H16FN2NaO2
Target-Kategorie:
Prostaglandin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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