Olezarsen, CAS [[2097587-83-0]]

Produktübersicht

• Artikelname: Olezarsen, CAS [[2097587-83-0]]
• Artikelnummer: MCE-HY-153491
• Hersteller Artikelnummer: HY-153491
• Alternativnummer: MCE-HY-153491-1MG,MCE-HY-153491-5MG,MCE-HY-153491-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: ISIS 678354, IONIS-APOCIII-LRx, AKCEA-APOCIII-LRx

Produktbeschreibung

Olezarsen (ISIS 678354, IONIS-APOCIII-LRx) is a GalNAc3-conjugated antisense oligonucleotide. Olezarsen binds to APOC3 mRNA and induces its degradation via ribonuclease H1-mediated sense strand cleavage, thereby reducing hepatic apolipoprotein C-III (apoC-III) synthesis. Olezarsen decreases plasma levels of triglycerides, apolipoprotein B and non-high-density lipoprotein cholesterol. Olezarsen is applicable to research related to familial chylomicronemia syndrome, hypertriglyceridemia and atherosclerotic cardiovascular disease[1].

Produkteigenschaften

• Molekulargewicht: 8684.86
• Reinheit: 96.53
• CAS Nummer: [2097587-83-0]
• Formel: C296H439N71O154P20S19
• Target-Kategorie: Apolipoprotein

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Oligonucleotides