Homo-BacPROTAC7 TFA is a PROTAC protein degrader targeting ClpC1/ClpC2 with a Kd of 0.5-2.5 nM for both targets. Homo-BacPROTAC7 (TFA) acts as a bactericidal agent, induces killing of pathogenic mycobacteria, retains activity against dormant-like mycobacterial cells with reduced intracellular ATP levels, and shows elevated antibiotic potency relative to its parent monomer. Homo-BacPROTAC7 (TFA) can be used for the research of tuberculosis[1].
Molekulargewicht:
2436.49
Reinheit:
99.03
Formel:
C111H150F12N22O26
Target-Kategorie:
Bacterial,PROTACs
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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