IPG7236, CAS [[2756350-91-9]]

Produktübersicht

• Artikelname: IPG7236, CAS [[2756350-91-9]]
• Artikelnummer: MCE-HY-153670
• Hersteller Artikelnummer: HY-153670
• Alternativnummer: MCE-HY-153670-100MG,MCE-HY-153670-10MG,MCE-HY-153670-50MG,MCE-HY-153670-25MG,MCE-HY-153670-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

IPG7236 is a selective and orally active CC chemokine receptor 8 (CCR8) antagonist with an IC50 of 24 nM in a Tango assay. IPG7236 effectively inhibits the downstream signaling of CCR8 induced by CCL1 (IC50 = 8.44 nM), CCL1-induced downstream signaling in the CCR8-overexpressing cells (IC50 = 24.3 nM), and CCL1-induced CCR8+ Treg cells migration (IC50 = 33.8 nM) .IPG7236 demonstrates an anti-cancer effect via up-regulating Treg and down-regulating cytotoxic T (CD8+ T) cells. IPG7236 can used for the study of breast cancer[1].

Produkteigenschaften

• Molekulargewicht: 429.58
• Reinheit: 98.54
• CAS Nummer: [2756350-91-9]
• Formel: C23H31N3O3S
• Target-Kategorie: CCR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound