KI-ARv-03, CAS [[2416873-72-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: KI-ARv-03, CAS [[2416873-72-6]] Preis auf Anfrage
• Artikelnummer: MCE-HY-153718
• Hersteller Artikelnummer: HY-153718
• Alternativnummer: MCE-HY-153718-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

KI-ARv-03 is a potent and selective ATP-competitive CDK9 inhibitor with an IC50 of 0.15 µM (at 45 µM ATP), exhibiting over 130-fold selectivity against other CDKs (including CDK1-7). KI-ARv-03 reduces androgen receptor (AR)-driven transcription and proliferation in prostate cancer cells. KI-ARv-03 can be used for leukemia, pancreatic cancer, alveolar rhabdomyosarcoma (ARMS) and castration-resistant prostate cancer (CRPC) research. KI-ARv-03 is a ligand for target protein for PROTAC. KI-ARv-03 can be used to synthesize PROTAC KI-CDK9d-32 (HY-173523)[1][2].

Produkteigenschaften

• Molekulargewicht: 259.35
• CAS Nummer: [2416873-72-6]
• Formel: C14H21N5
• Target-Kategorie: CDK,c-Myc,Ligands for Target Protein for PROTAC

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound