UC-764864 is a selective UBE2N inhibitor. UC-764864 covalently binds UBE2N catalytic Cys87, blocks ubiquitin-UBE2N thioester formation and polyubiquitin chain synthesis. UC-764864 blocks ubiquitination of innate immune- and inflammatory-related substrates, and induces cell apoptosis. UC-764864 can be used for the research of acute myeloid leukemia[1].
Molekulargewicht:
322.42
Reinheit:
99.89
CAS Nummer:
[278806-03-4]
Formel:
C19H18N2OS
Target-Kategorie:
Apoptosis,E1/E2/E3 Enzyme
Anwendungsbeschreibung:
MCE Product type: Reference compound
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