URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1, with IC50 of 3.3 µM for xanthine oxidase. URAT1&XO inhibitor 2 blocks uptake of uric acid in HEK293 cells expressing URAT1, with a Ki value of 0.145 µM. URAT1&XO inhibitor 2 decreases serum urate level and uric acid excretion in hyperuricemic mice. URAT1&XO inhibitor 2 can be used for research of hyperuricemia[1].
Molekulargewicht:
322.15
Reinheit:
98.69
CAS Nummer:
[1239488-96-0]
Formel:
C14H12BrNO3
Target-Kategorie:
URAT1,Xanthine Oxidase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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