Darusentan, CAS [[171714-84-4]]

Produktübersicht

• Artikelname: Darusentan, CAS [[171714-84-4]]
• Artikelnummer: MCE-HY-15404
• Hersteller Artikelnummer: HY-15404
• Alternativnummer: MCE-HY-15404-1MG,MCE-HY-15404-10MG,MCE-HY-15404-50MG,MCE-HY-15404-25MG,MCE-HY-15404-100MG,MCE-HY-15404-10MMX1ML,MCE-HY-15404-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: Lu-135252

Produktbeschreibung

Darusentan (Lu-135252) is a selective endothelin receptor A (ET-A) receptor antagonist, which binds with a Ki of 1.4 nM to the ET-A receptor and a Ki of 184 nM to ET-B receptor, respectively with a 100-fold selectivity for ETA rather than ETB receptors[1]. Darusentan competes for radiolabeled endothelin binding in rat aortic vascular smooth muscle cells (RAVSMs) membranes with single-site kinetics, exhibiting a Ki of 13 nM[2].

Produkteigenschaften

• Molekulargewicht: 410.42
• Reinheit: 98.67
• CAS Nummer: [171714-84-4]
• Formel: C22H22N2O6
• Target-Kategorie: Endothelin Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound