5'-Azido-5'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 5'-Azido-5'-deoxyadenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Molekulargewicht:
292.25
CAS Nummer:
[737-76-8]
Formel:
C10H12N8O3
Target-Kategorie:
Nucleoside Antimetabolite/Analog
Anwendungsbeschreibung:
MCE Product type: Oligonucleotides
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