Basimglurant (Standard), CAS [[802906-73-6]]

Produktübersicht

• Artikelname: Basimglurant (Standard), CAS [[802906-73-6]]
• Artikelnummer: MCE-HY-15446R
• Hersteller Artikelnummer: HY-15446R
• Alternativnummer: MCE-HY-15446R-50MG,MCE-HY-15446R-1MG,MCE-HY-15446R-5MG,MCE-HY-15446R-10MG,MCE-HY-15446R-25MG,MCE-HY-15446R-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: RG7090 (Standard), RO4917523 (Standard)

Produktbeschreibung

Basimglurant (RG7090, RO4917523) (Standard) is the analytical standard of Basimglurant. This product is intended for research and analytical applications. Basimglurant is a selective, orally active, blood-brain barrier permeable negative allosteric modulator of metabotropic glutamate receptor 5 (mGluR5), with a Ki of 1.4 nM (against [3H]-ABP688 (HY-110141)) and 35.6 nM (against [3H]-MPEP (HY-14609A)). Basimglurant inhibits mGlu5-mediated signaling pathways and receptor constitutive activity, regulates dopamine levels in the nucleus accumbens, exerts anxiolytic, antidepressant-like, analgesic and arousal-promoting effects, and alters delta-wave power during non-rapid eye movement sleep. Basimglurant can be used in research on depression, fragile X syndrome, anxiety disorders, etc.[1][2]

Produkteigenschaften

• Molekulargewicht: 325.77
• CAS Nummer: [802906-73-6]
• Formel: C18H13ClFN3
• Target-Kategorie: mGluR,Reference Standards

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference Standards