PRX-08066, CAS [[866206-54-4]]

Produktübersicht

• Artikelname: PRX-08066, CAS [[866206-54-4]]
• Artikelnummer: MCE-HY-15472
• Hersteller Artikelnummer: HY-15472
• Alternativnummer: MCE-HY-15472-5MG,MCE-HY-15472-1MG,MCE-HY-15472-25MG,MCE-HY-15472-10MG,MCE-HY-15472-10MMX1ML,MCE-HY-15472-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PRX-08066 is a selective and orally active 5-hydroxytryptamine receptor 2B (5-HT2BR) antagonist with a Ki of 3.4 nM. PRX-08066 inhibits the MAPK pathway, 5-HT release and fibrotic factor (TGFbeta1, CTGF and FGF2) expression. PRX-08066 inhibits the proliferation of KRJ-I cells and induces apoptosis (caspase-3 activation). PRX-08066 inhibits pulmonary vascular remodeling. PRX-08066 can be used of pulmonary Arterial Hypertension (PAH) and neuroendocrine tumor (NET)[1][2].

Produkteigenschaften

• Molekulargewicht: 401.89
• Reinheit: 97.46
• CAS Nummer: [866206-54-4]
• Formel: C19H17ClFN5S
• Target-Kategorie: 5-HT Receptor,Apoptosis,Caspase,FGFR,p38 MAPK,TGF-beta Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound