Os30, CAS [[2998928-68-8]]

Produktübersicht

• Artikelname: Os30, CAS [[2998928-68-8]]
• Artikelnummer: MCE-HY-155358
• Hersteller Artikelnummer: HY-155358
• Alternativnummer: MCE-HY-155358-25MG,MCE-HY-155358-50MG,MCE-HY-155358-10MG,MCE-HY-155358-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Os30, a potent fourth-generation EGFR inhibitor, is a potent EGFRC797S-TK inhibitor with IC50 values of 18 nM and 113 nM for EGFRDel19/T790M/C797S TK and EGFRL858R/T790M/C797S TK, respectively. Os30 can suppress EGFR phosphorylation, arrest at G1 phase and induce the apoptosis of KC-0116 (BaF3-EGFRDel19/T790M/C797S) cells. Os30 shows potent antitumor efficacy on non-small cell lung cancer (NSCLC) with EGFmRC797S mutation[1].

Produkteigenschaften

• Molekulargewicht: 519.66
• Reinheit: 98.34
• CAS Nummer: [2998928-68-8]
• Formel: C27H33N7O2S
• Target-Kategorie: Apoptosis,EGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound