VEGFR-2/AURKA-IN-1 (compound 5e) is a thiazolidin-4-one derivative with antiglioma activity (IC50: 6.43 µM, LN229). VEGFR-2/AURKA-IN-1 has affinity for AURKA and VEGFR-2 and is a potential ligand. VEGFR-2/AURKA-IN-1 causes DNA strand breaks and exhibits cytotoxic and anticancer potential[1].
Molekulargewicht:
528.85
Formel:
C20H15ClF6N2O4S
Target-Kategorie:
Aurora Kinase,VEGFR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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