ERalpha degrader 7 (compound B1) is a potent ERalpha degrader with an IC50 of 14.6 nM and a DC50 of 9.7 nM, respectively. ERalpha degrader 7 shows excellent antitumor activity, indicating its potential to evolve as a promising selective estrogen-receptor degrader (SERD) for breast cancer research[1].
Molekulargewicht:
512.50
Formel:
C28H24F4N2O3
Target-Kategorie:
Estrogen Receptor/ERR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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