Cisd2 agonist 2 (compound 6) is a Cisd2 activator (EC50=191 nM), and Cisd2 levels are associated with non-alcoholic fatty liver disease (NAFLD). Cisd2 agonist 2 has no significant in vivo toxicity in Cisd2hKO-het mice (heterozygous hepatocyte-specific Cisd2 knockout). Cisd2 (CDGSH iron sulfur domain 2) is a zinc finger protein that is mainly localized in the endoplasmic reticulum or mitochondrial membrane. Cisd2 participates in mitochondrial function by forming homodimers containing two redox-active 2Fe-2S clusters[1][2].
Molekulargewicht:
306.34
Reinheit:
99.17
CAS Nummer:
[2916371-59-8]
Formel:
C14H14N2O4S
Target-Kategorie:
IKZF Family,Zinc Finger Protein
Anwendungsbeschreibung:
MCE Product type: Reference compound
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