SCAL-255 is a potent mitochondrial complex I (CI) inhibitor with an IC50 of 1.14 µM. SCAL-255 blocks mitochondrial function, inhibits oxygen consumption rate (OCR), induces reactive oxygen species (ROS) production, and reduces MMP. SCAL-255 can be used in the research of oxidative phosphorylation (OXPHOS)-dependent cancers, such as colorectal cancer (CRC) and acute myeloid leukemia (AML), etc[1].
Molekulargewicht:
527.54
Reinheit:
99.15
CAS Nummer:
[2798953-61-2]
Formel:
C27H28F3N5O3
Target-Kategorie:
Mitochondrial Metabolism,MMP,Oxidative Phosphorylation,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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