PK-10 is a synergistic antibacterial agent of Fluconazole (HY-B0101) and has strong antifungal activity against a variety of Fluconazole-resistant Candida albicans strains. PK-10 combined with Fluconazole can inhibit hyphae formation and induce the accumulation of reactive oxygen species. It further causes damage to mitochondrial membrane potential, reduces intracellular ATP content, and leads to mitochondrial dysfunction[1].
Molekulargewicht:
599.69
CAS Nummer:
[3074451-41-2]
Formel:
C35H36F3N5O
Target-Kategorie:
Fungal,Mitochondrial Metabolism
Anwendungsbeschreibung:
MCE Product type: Reference compound
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