mHTT-IN-2, CAS [[2743336-70-9]]

Produktübersicht

• Artikelname: mHTT-IN-2, CAS [[2743336-70-9]]
• Artikelnummer: MCE-HY-156103
• Hersteller Artikelnummer: HY-156103
• Alternativnummer: MCE-HY-156103-50MG,MCE-HY-156103-25MG,MCE-HY-156103-10MG,MCE-HY-156103-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

mHTT-IN-2 (compound 27) is a potent inhibitor (EC50=0.066 µM) of mutant huntingtin (mHTT). mHTT-IN-2 reduces canonical splicing of HTT RNA exons [49-50] and is a splicing regulator of the huntingtin (HTT) gene. mHTT-IN-2 exhibits inhibitory activity in vitro and in vivo in human HD stem cells and mouse BACHD models. mHTT-IN-2 may be used in the study of branaplam-related peripheral neuropathy[1].

Produkteigenschaften

• Molekulargewicht: 395.43
• Reinheit: 99.35
• CAS Nummer: [2743336-70-9]
• Formel: C20H22FN7O
• Target-Kategorie: Huntingtin

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound