NSC194598, CAS [[5358-76-9]]

Produktübersicht

• Artikelname: NSC194598, CAS [[5358-76-9]]
• Artikelnummer: MCE-HY-156135
• Hersteller Artikelnummer: HY-156135
• Alternativnummer: MCE-HY-156135-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

NSC194598 is a p53 DNA-binding inhibitor with an IC50 value of 180 nM. NSC194598 inhibits p53 DNA binding and induction of target genesn when p53 is stabilized and activated by irradiation or chemotherapy. NSC194598 can interfere with transcriptional activation of mutated rearranged during transfection (RET) gene, induce apoptosis and G0/G1 phase arrest. NSC194598 can be used for the researches of acute radiation toxicity and medullary thyroid carcinoma[1][2].

Produkteigenschaften

• Molekulargewicht: 317.38
• Reinheit: 98.90
• CAS Nummer: [5358-76-9]
• Formel: C20H19N3O
• Target-Kategorie: Apoptosis,Caspase,DNA/RNA Synthesis,MDM-2/p53,RET

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound