PAK4-IN-3(compound 27e) is aPAK4inhibitor, with theIC50of 10 nM.PAK4-IN-3shows antiproliferative activity against A549 cells with anIC50value of 0.61µM, and inducesapoptosisof A549 cells in a concentration-dependent manner and blocked the cell cycle at phase G0/G1[1].
Molekulargewicht:
423.90
Formel:
C21H22ClN7O
Target-Kategorie:
Apoptosis,PAK
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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