pan-KRAS-IN-2 (Compound 6) is a pan-inhibitor with IC50s 10 nM for KRAS WT and mutants (G12D, G12C, G12V, G12S, G12A and Q61H), and an IC50 > 10 µM for KRAS G13D. pan-KRAS-IN-2 can be used to study various KRAS-mediated cancers, such as pancreatic cancer and colorectal cancer[1].
Molekulargewicht:
584.66
Reinheit:
98.01
CAS Nummer:
[2882825-14-9]
Formel:
C34H34F2N4O3
Target-Kategorie:
Ras
Anwendungsbeschreibung:
MCE Product type: Reference compound
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