FM19G11 is a hypoxia-inducible factor-1-alpha (HIF-1alpha) inhibitor, and it inhibits hypoxia-induced luciferase activity with an IC50 of 80 nM in HeLa cells. FM19G11 modulates other signaling pathways, including mTOR and PI3K/Akt/eNOS, when the HIF-1alpha pathway is inactivated under normoxic conditions[1][2].
Molekulargewicht:
463.40
Reinheit:
98.39
CAS Nummer:
[329932-55-0]
Formel:
C23H17N3O8
Target-Kategorie:
HIF/HIF Prolyl-Hydroxylase
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
