Poziotinib, CAS [[1092364-38-9]]

Produktübersicht

• Artikelname: Poziotinib, CAS [[1092364-38-9]]
• Artikelnummer: MCE-HY-15730
• Hersteller Artikelnummer: HY-15730
• Alternativnummer: MCE-HY-15730-5MG,MCE-HY-15730-100MG,MCE-HY-15730-10MMX1ML,MCE-HY-15730-10MG,MCE-HY-15730-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: HM781-36B, NOV120101

Produktbeschreibung

Poziotinib (HM781-36B) is an orally active, irreversible pan-HER inhibitor, which effectively inhibits EGFRwt, HER-2 and HER-4 with IC50s of 3.2, 5.3 and 23.5 nM, respectively. Poziotinib (HM781-36B) also shows excellent inhibitory activities against mutated EGFRs, including EGFRT790M and EGFRL858R/T790M, with IC50s of 4.2 and 2.2 nM, respectively. Excellent antitumor activity[1][2].

Produkteigenschaften

• Molekulargewicht: 491.34
• Reinheit: 99.96
• CAS Nummer: [1092364-38-9]
• Formel: C23H21Cl2FN4O3
• Target-Kategorie: Apoptosis,EGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound