EGFR T790M/L858R-IN-3 (compound B1) is a EGFRL858R/T790M inhibitor with IC50 value of 13 nM. EGFR T790M/L858R-IN-3 shows anti-tumour activity in H1975 cells with an IC50 value of 0.087 µM. EGFR T790M/L858R-IN-3 inhibits cell migration in A549 cells and induces apoptosis in H1975 cells[1].
Molekulargewicht:
598.18
Formel:
C28H32ClN7O2S2
Target-Kategorie:
EGFR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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