MS154N (compound 28) is the negative control of MS39 (HY-157581). MS154N is composed of PROTAC target protein ligand EGFR ligand-11 (HY-168305) (red part), E3 ligase ligand 4-Hydroxy-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione (HY-W441376) (blue part) and PROTAC Linker 8-Iodooctan-1-amine (HY-168306) (black part), among which the conjugate of E3 ubiquitin ligase ligand + Linker is Me-Thalidomide-O-C8-NH2 (HY-168307)[1].
Molekulargewicht:
915.45
Reinheit:
99.30
CAS Nummer:
[2675490-97-6]
Formel:
C47H56ClFN8O8
Target-Kategorie:
EGFR,PROTACs
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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