LTGO-33, CAS [[2834106-06-6]] Preis auf Anfrage

Artikelnummer: MCE-HY-157802
Artikelname: LTGO-33, CAS [[2834106-06-6]] Preis auf Anfrage
Artikelnummer: MCE-HY-157802
Hersteller Artikelnummer: HY-157802
Alternativnummer: MCE-HY-157802-50MG,MCE-HY-157802-5MG,MCE-HY-157802-100MG,MCE-HY-157802-10MG,MCE-HY-157802-10MMX1ML,MCE-HY-157802-25MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
LTGO-33 is a potent and selective voltage-gated sodium channel NaV1.8 inhibitor. LTGO-33 inhibits NaV1.8 in the nM potency range and exhibits over 600-fold selectivity against human NaV1.1-NaV1.7 and NaV1.9. LTGO-33 exhibits state-independent inhibition with similar potencies on channels in the closed and inactivated conformations. LTGO-33 inhibits native TTX-R NaV1.8 currents in non-human primate and human DRG neurons, where it reduces action potential firing. LTGO-33 can be used for pain disorders research[1].
Molekulargewicht: 467.44
Reinheit: 98.83
CAS Nummer: [2834106-06-6]
Formel: C21H17F4N3O3S
Target-Kategorie: Sodium Channel
Anwendungsbeschreibung: MCE Product type: Reference compound